Protective Activity of Aqueous Extracts from Higher Mushrooms Against Herpes sipmlex Virus Type-2 on Albino Mice Model

Protective Activity of Aqueous Extracts from Higher Mushrooms Against Herpes sipmlex Virus Type-2 on Albino Mice Model

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Toxicity and antiviral activity of aqueous extracts from higher mushrooms such as Lentinula edodes (Berk.) Pegler (shiitake), Pleurotus ostreatus (Jacq.) P.Kumm.

(oyster), Football - Protective - Shoulder Pads Inonotus obliquus (Ach.ex Pers.) Pilat (chaga), Hydnellum compactum (Pers.) P.

Karst.(compact tooth) were studied.In doses of 0.8 to 4.

0 mg (dry weight) per mouse administered orally or intraperitoneally the extracts showed no acute toxicity.When the dose of the chaga extract was increased to 20 mg per mouse, a half of the animals died.Intraperitoneal administration of the aqueous extracts in a dose of 0.4-2 mg per mouse prior to the contamination by a single LD50 of Herpes simplex type 2 provided 100-percent survival of the animals exposed ACTIVATED CHARCOAL PEPPERMINT to the Lentinula edodes or Pleurotus ostreatus extracts and 90-percent survival of the animals exposed to the Inonotus obliquus or Hydnellum compactum extracts.